To phenotype major echo-cardiovascular biomarkers (cardiac dilation,
cardiac index, blood pressure, diastolic dysfunction, tricuspid jet regurgitation velocity
(TRJV) and RV dysfunction) in 2,000 adults with SCD patients from West and East
Africa. To catalogue genetic variants associated with the aforementioned echo-
cardiovascular phenotypes in adult SCD patient. To determine whether polymorphism
associated with HCP levels are linked to specific echo-cardiovascular phenotypes.